Damaged Heart Muscles Salisbury MD

Researchers have genetically engineered cells that help form scar tissue after a heart attack into a type of cell that does just the opposite -- repairs damage to the heart muscle.

Stephan Pavlos, MD
(410) 749-8906
5405 Royal Mile Blvd
Salisbury, MD
Specialties
Cardiology, Internal Medicine
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1986
Hospital
Hospital: Peninsula Regional Med Center, Salisbury, Md
Group Practice: Peninsula Cardiology Associates Pa

Data Provided by:
John Robert Mc Lean, MD
(410) 749-4949
440 Rolling Rd
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1978

Data Provided by:
Anthony J Frey
(410) 341-0300
1205 Pemberton Dr
Salisbury, MD
Specialty
Cardiology, Cardiovascular Disease

Data Provided by:
Harikisan Ramibilas Heda, MD
(410) 749-5419
1109 Riverside Dr
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Indira Ghandi Med Coll, Nagpur Univ, Nagpur, Maharashtra, India
Graduation Year: 1971

Data Provided by:
Bal K Agarwal, MD
(410) 749-5419
5450 Royal Mile Blvd
Salisbury, MD
Specialties
Internal Medicine, Cardiovascular Diseases
Gender
Male
Education
Medical School: Sawai Man Singh Med Coll, Univ Of Rajast
Graduation Year: 1963

Data Provided by:
Ramesh K Agarwal
(410) 749-4999
145 E Carroll St
Salisbury, MD
Specialty
Cardiology, Cardiovascular Disease

Data Provided by:
Benjamin H Meyer, MD, FACC
(410) 749-8942
26283 High Banks Dr
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Tomasz A Swierkosz, MD
(410) 546-2480
26377 Manchester Ct
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Coll Med, Univ Jagiellonski, Krakow, Poland
Graduation Year: 1989

Data Provided by:
Steven Edward Hearne, MD
(410) 546-1670
5417 Royal Mile Blvd
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1989

Data Provided by:
Joseph Alan Cinderella, MD
(410) 334-2227
100 E Carroll St
Salisbury, MD
Specialties
Cardiology, Internal Medicine
Gender
Male
Education
Medical School: Univ Of Mi Med Sch, Ann Arbor Mi 48109
Graduation Year: 1985
Hospital
Hospital: Peninsula Regional Med Center, Salisbury, Md; Atlantic Gen Hosp, Berlin, Md
Group Practice: Mc Lean Frey & Assoc

Data Provided by:
Data Provided by:

Damaged Heart Muscles

Provided By:

Researchers have genetically engineered cells that help form scar tissue after a heart attack into a type of cell that does just the opposite -- repairs damage to the heart muscle, a new study in mice shows.

The research team from the Mayo Clinic in Rochester, Minn., reprogrammed fibroblasts -- cells that play a role in scarring -- into becoming induced pluripotent stem (iPS) cells, which are stem cells that have been converted from adult cells.

The iPS cells were then transplanted into damaged mouse hearts, where they engrafted after two weeks. After four weeks, the mice hearts had improved structure and function, according to the study authors.

The iPS cells improved heart muscle performance, halted progression of structural damage to the already damaged heart and regenerated tissue at the site of damage, the researchers said.

"This study establishes the real potential for using iPS cells in cardiac treatment," study author Dr. Timothy Nelson said in a Mayo Clinic news release. "Bioengineered fibroblasts acquired the capacity to repair and regenerate infarcted hearts."

This study, which is reported online in the journal Circulation, was the first time iPS cells were used to repair heart tissue. Previous studies have investigated using iPS cells to treat Parkinson's disease, sickle cell anemia and hemophilia A.

Because iPS cells are derived from the patient, there is no risk of rejection or need for anti-rejection drugs, the researchers noted.

The hope is to one day be able to use iPS cells to repair injuries, helping to alleviate the demand for organ transplantation.

"This iPS innovation lays the groundwork for translational applications," senior study author Dr. Andre Terzic, Mayo Clinic physician-scientist, said in the same news release.

More information

The American Heart Association has more on heart attacks.

SOURCE: Mayo Clinic, news release, July 20, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com