Effects of Long-Term Lead Exposure Salisbury MD

Exposure to lead over a lifetime may increase the risk of dying from heart disease, new research shows. Researchers analyzed lead concentrations in the blood and bones of 868 mostly white men from the Boston area who participated in a veterans' aging study.

John Robert Mc Lean, MD
(410) 749-4949
440 Rolling Rd
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1978

Data Provided by:
Anthony J Frey
(410) 341-0300
1205 Pemberton Dr
Salisbury, MD
Specialty
Cardiology, Cardiovascular Disease

Data Provided by:
Joseph Alan Cinderella, MD
(410) 334-2227
100 E Carroll St
Salisbury, MD
Specialties
Cardiology, Internal Medicine
Gender
Male
Education
Medical School: Univ Of Mi Med Sch, Ann Arbor Mi 48109
Graduation Year: 1985
Hospital
Hospital: Peninsula Regional Med Center, Salisbury, Md; Atlantic Gen Hosp, Berlin, Md
Group Practice: Mc Lean Frey & Assoc

Data Provided by:
Tomasz A Swierkosz, MD
(410) 546-2480
26377 Manchester Ct
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Coll Med, Univ Jagiellonski, Krakow, Poland
Graduation Year: 1989

Data Provided by:
Anthony Jay Frey, MD
(410) 749-4949
5454 Royal Mile Blvd
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Suny-Hlth Sci Ctr At Brooklyn, Coll Of Med, Brooklyn Ny 11203
Graduation Year: 1990

Data Provided by:
Stephan Pavlos, MD
(410) 749-8906
5405 Royal Mile Blvd
Salisbury, MD
Specialties
Cardiology, Internal Medicine
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1986
Hospital
Hospital: Peninsula Regional Med Center, Salisbury, Md
Group Practice: Peninsula Cardiology Associates Pa

Data Provided by:
Bal K Agarwal, MD
(410) 749-5419
5450 Royal Mile Blvd
Salisbury, MD
Specialties
Internal Medicine, Cardiovascular Diseases
Gender
Male
Education
Medical School: Sawai Man Singh Med Coll, Univ Of Rajast
Graduation Year: 1963

Data Provided by:
Steven Edward Hearne, MD
(410) 546-1670
5417 Royal Mile Blvd
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1989

Data Provided by:
Ramesh Kumar Agarwal, MD
(410) 341-0300
5519 E Nithsdale Dr
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Medical School: Patna Med Coll, Patna Univ, Bihar, India
Graduation Year: 1987

Data Provided by:
Benjamin H Meyer, MD, FACC
(410) 749-8942
26283 High Banks Dr
Salisbury, MD
Specialties
Cardiology
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Data Provided by:

Effects of Long-Term Lead Exposure

Provided By:

TUESDAY, Sept. 8 (HealthDay News) -- Exposure to lead over a lifetime may increase the risk of dying from heart disease, new research shows.

Researchers analyzed lead concentrations in the blood and bones of 868 mostly white men from the Boston area who participated in a veterans' aging study.

The men, whose average age was 67 at the start of the study, had lead concentrations in their blood and the bones of the patella (kneecap) and tibia (shin) measured over a nine-year period. During the course of the study, 241 died.

Researchers found that men who had the highest concentrations of lead in their bones had a six times greater chance of dying from cardiovascular disease than men with the lowest concentrations.

Men with the highest levels of lead had a 2.5 times greater chance of dying from all causes than men with the lowest levels.

"Cumulative exposure to lead, even in an era when current exposures are low, represents an important predictor of cardiovascular death," said study author Marc Weisskopf, an assistant professor of environmental health and epidemiology at the Harvard School of Public Health in Boston. "The findings with bone lead are dramatic. It is the first time we have had a biomarker of cumulative exposure to lead, and the strong findings suggest that it is a more critical biomarker than blood lead."

The study appears in the Sept. 8 issue of Circulation.

Typically, lead exposure is measured through blood samples. For instance, the Occupational Safety and Health Administration (OSHA) and the National Health and Nutrition Examination Surveys use blood to measure lead.

But blood, because it has a half life of about 30 days, reveals recent exposure. To determine cumulative exposure, bone is the better method, according to the study.

Bone has a half life ranging from years to decades, including eight years in the knee cap and possibly decades in the shin. To determine bone lead concentration, researchers used a technique similar to a chest X-ray.

Researchers said the link to cardiovascular disease underscores the need for regulatory bodies and surveillance agencies to track potential sources of lead exposure.

"Researchers studying cardiovascular deaths worldwide have generally not considered lead as one of the risk factors that contributes to the risk of death from cardiovascular disease," Weisskopf said.

Overall, study participants had blood levels of lead that were slightly higher than the average of similar U.S. men.

While few if any participants in the study were occupationally exposed to lead, occupations such as construction and painting put men at higher risk.

The current OSHA standards, which are based on blood lead levels and permit up to 40 micrograms of lead per deciliter, are probably inadequate, Weisskopf said.

Before being banned in the mid-1990s, leaded gasoline was a major source of U.S. environmental lead exposure.

Current sources of exposure are chipping, flaking lead in paint in older homes, water pipes in older homes, lead in food and drinking water and hobbies that involve casting ammunition, toy soldiers, fishing weights, lead in solder for making stained glass and some ceramic glazes.

More information

The American Academy of Family Physicians has more on lead exposure.

SOURCE: American Heart Association, news release, Sept. 8, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com