Gene Mutation in Dogs Arlington VA

A genetic mutation that causes a neurological disorder called sensory ataxic neuropathy (SAN) in Golden Retriever dogs in Arlington has been identified by Swedish scientists. Dogs with SAN have uncoordinated movement and sensory problems. The symptoms appear when affected dogs are puppies.

Max & Ruffy's
(703) 465-4481
PO Box 100605
Arlington, VA

Data Provided by:
GreenPets
(202) 986-7907
1722 14th Street NW
Washington, DC

Data Provided by:
Organic Doggy Kitchen
(703) 532-7387
1061B West Broad St
Falls Church, VA

Data Provided by:
Aunt Jeni's Home Made
(301) 702-0123
PO Box 124
Temple Hills, MD

Data Provided by:
NalaBone Inc. EcoSafe Biodegradable Plastic Bags
(571) 345-4903
3505 Mavis Court
Fairfax, VA

Data Provided by:
The Dog Chef
(301) 785-2998
3901 tunlaw rd nw suite 102
Washington, DC

Data Provided by:
Pet Pantry
(202) 363-6644
4455 Connecticut Ave., NW
Washington, DC

Data Provided by:
The Big Bad Woof
(202) 291-2404
117 Carroll St., NW
Washington, DC

Data Provided by:
Happy Woof
(703) 967-0465
10396 Willard Way
Fairfax, VA
Products
Va. We offer a three tub self serve dog wash
Hours
full service grooming

PetSmart
(703) 739-4844
3351 Jefferson Davis Hwy
Alexandria, VA
Hours
Monday - Friday: 9:00-9:00
Sunday: 10:00-6:00

Data Provided by:

Gene Mutation in Dogs

Provided By:

FRIDAY, May 29 (HealthDay News) -- A genetic mutation that causes a neurological disorder called sensory ataxic neuropathy (SAN) in Golden Retriever dogs has been identified by Swedish scientists.

Dogs with SAN have uncoordinated movement and sensory problems. The symptoms appear when affected dogs are puppies.

The Swedish team found that SAN is caused by a one-base pair deletion in the mitochondrial tRNA-Tyr gene. The mutation leads to mitochondrial dysfunction, which causes a progressive loss of neurons.

Identification of the mutation enables genetic screening tests to identify carriers and prevent transmission of the mutation to future generations, the researchers suggested.

The study findings, published in the journal PLoS Genetics on May 29, may also help scientists research similar mitochondrial disorders in humans and could potentially be used to test new therapies, the study authors note in the release.

"This is a good example of how a close collaboration between clinicians and geneticists led to a rapid detection of a harmful mutation that can now be eliminated from this dog population to reduce suffering and disease," study co-author Karin Hultin Jaderlund said in a journal news release.

More information

Johns Hopkins University provides details about sensory ataxic neuropathy.

SOURCE: Public Library of Science, news release, May 28,2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com