Gene Mutation in Dogs Salisbury MD

A genetic mutation that causes a neurological disorder called sensory ataxic neuropathy (SAN) in Golden Retriever dogs in Salisbury has been identified by Swedish scientists. Dogs with SAN have uncoordinated movement and sensory problems. The symptoms appear when affected dogs are puppies.

PetSmart
(410) 546-4822
105 E North Pointe Blvd
Salisbury, MD
Hours
Monday - Friday: 9:00-9:00
Sunday: 10:00-6:00

Birds Of Choice
(877) 300-3531
38199 Whaleys Road
Delmar, DE
 
{Hairless Gems} hairless spyhnx cats for sale by breeder
(410) 845-9262
delmar delaware
delmar, DE
 
Hickory Pet Supply
(410) 838-7797
534 E. Jarrettsville Rd
Forest Hill, MD

Data Provided by:
Bark!
(443) 535-0200
5805 Clarksville Sq. Dr. Ste. 4
Clarksville, MD

Data Provided by:
PetSmart
(410) 546-4822
105 E North Pointe Dr
SALISBURY, MD

Data Provided by:
HAIRLESS GEMS HAS HAIRLESS SPYHNX CATS
(302) 604-7573
DELMAR DELAWARE
DELMAR, DE
Prices and/or Promotions
$450.00

Central Dawgma
(301) 846-7771
1202 East Patrick Street
Frederick, MD

Data Provided by:
Aunt Jeni's Home Made
(301) 702-0123
PO Box 124
Temple Hills, MD

Data Provided by:
Two Paws Up
(301) 668-7704
15 South Carroll Street
Frederick, MD

Data Provided by:
Data Provided by:

Gene Mutation in Dogs

Provided By:

FRIDAY, May 29 (HealthDay News) -- A genetic mutation that causes a neurological disorder called sensory ataxic neuropathy (SAN) in Golden Retriever dogs has been identified by Swedish scientists.

Dogs with SAN have uncoordinated movement and sensory problems. The symptoms appear when affected dogs are puppies.

The Swedish team found that SAN is caused by a one-base pair deletion in the mitochondrial tRNA-Tyr gene. The mutation leads to mitochondrial dysfunction, which causes a progressive loss of neurons.

Identification of the mutation enables genetic screening tests to identify carriers and prevent transmission of the mutation to future generations, the researchers suggested.

The study findings, published in the journal PLoS Genetics on May 29, may also help scientists research similar mitochondrial disorders in humans and could potentially be used to test new therapies, the study authors note in the release.

"This is a good example of how a close collaboration between clinicians and geneticists led to a rapid detection of a harmful mutation that can now be eliminated from this dog population to reduce suffering and disease," study co-author Karin Hultin Jaderlund said in a journal news release.

More information

Johns Hopkins University provides details about sensory ataxic neuropathy.

SOURCE: Public Library of Science, news release, May 28,2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com