Heart Damage Treatments Alexandria VA

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

Richard Hart, MD
(703) 241-1010
6400 Arlington Blvd
Falls Church, VA
Business
MSG of NOVA
Specialties
Cardiology

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Steinmetz Medical Associates
(703) 671-2700
1225 Martha Custis Drive, Suite C-1
Alexandria, VA
Services
Women's Health, Preventive Medicine, Homeopathy, Herbal Medicine, Gynecology, Functional Medicine, Family Practice, Diabetes, Cardiovascular Disease, Bio-identical HRT, Acupuncture
Membership Organizations
American Holistic Medical Association

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Paul Stephen Massimiano, MD
(703) 280-1473
4320 Seminary Rd
Alexandria, VA
Specialties
Cardiology, Vascular Surgery
Gender
Male
Education
Medical School: Georgetown Univ Sch Of Med, Washington Dc 20007
Graduation Year: 1978

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Paul John O Brien
(703) 823-6904
4660 Kenmore Avenue
Alexandria, VA
Specialty
Cardiology, Cardiovascular Disease

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Jeffrey A Jackman
(703) 751-8111
4660 Kenmore Ave
Alexandria, VA
Specialty
Cardiology, Cardiovascular Disease

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Robert Lawrence McSwain, MD
(703) 208-9797
5902 Mount Eagle Dr Apt 911
Alexandria, VA
Specialties
Cardiology
Gender
Male
Education
Medical School: Med Coll Of Ga Sch Of Med, Augusta Ga 30912
Graduation Year: 1996

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Lawrence Allan Miller, MD
(703) 751-8111
4660 Kenmore Ave Ste 1200
Alexandria, VA
Specialties
Cardiology
Gender
Male
Education
Medical School: Suny At Buffalo Sch Of Med & Biomedical Sci, Buffalo Ny 14214
Graduation Year: 1976

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Stephen M Day
(703) 751-8111
4660 Kenmore Ave
Alexandria, VA
Specialty
Cardiology, Cardiovascular Disease

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Paul John O'Brien, MD
(703) 751-6668
4660 Kenmore Ave Ste 800
Alexandria, VA
Specialties
Cardiology
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1986

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Keith Michael Sterling, MD
(703) 751-7200
6355 Walker Ln
Alexandria, VA
Specialties
Radiology, Cardiovascular Diseases
Gender
Male
Education
Medical School: New York Med Coll, Valhalla Ny 10595
Graduation Year: 1989
Hospital
Hospital: Potomac Hospital, Woodbridge, Va; Inova Alexandria Hospital, Alexandria, Va; Inova Fair Oaks Hospital, Fairfax, Va
Group Practice: Assn Of Alexandria Radiologist; Association Of Alexandra Radiologists Pc; Association Of Alexandria Radiologist

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Heart Damage Treatments

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Doctors have been unable to help injured heart tissue renew itself after a heart attack -- until now.

During a heart attack, vessels that supply blood to the heart become blocked, preventing enough oxygen from getting through. The heart muscle dies or is permanently damaged.

But researchers at Children's Hospital Boston report progress toward someday being ale to regenerate heart tissue after a heart attack or heart failure and even in children who are born with congenital heart defects.

In a study on mice, they showed that neuregulin 1 (NRG1), a growth factor involved in the development of the heart and nervous system, can fuel heart-muscle growth and recovery of cardiac function when injected after a heart attack.

This is a significant development because coronary heart disease, which causes heart attack and angina, is the leading cause of death in America.

After birth, heart-muscle cells stop dividing and proliferating. But experts, led by Dr. Bernhard Kuhn and Kevin Bersell of the cardiology department at Children's, restarted the cell cycle with NRG1, spurring the heart-muscle cells to divide and make copies of themselves.

When the team injected NRG1 into live mice once a day for three months after the animals had heart attacks, heart regeneration increased and the pumping function improved, compared with untreated mice.

In addition, the NRG1-injected mice did not show some common aftereffects of heart failure.

The study, funded by the cardiology department at Children's Hospital Boston, the Charles Hood Foundation and the American Heart Association, found that cell growth does not have to come from stem cells. A report on the research appears in the July 24 issue of Cell.

"Although many efforts have focused on stem cell-based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes [heart-muscle cells] to proliferate may be a viable alternative," Kuhn, the study's senior investigator, said in a news release from the hospital.

More information

The American Heart Association has tips on maintaining a healthy heart.

SOURCE: Children's Hospital Boston, news release, July 23, 2009

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